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Longevity

Ayushi Joshi

Graphic design intern

November 06, 2024

Summary "Elderly-centric chromatics: Unraveling the color preferences and visual needs of the elderly in smart app interfaces."

The study, "Elderly-centric chromatics: unraveling the color preferences and visual needs of the elderly in smart app interfaces," addresses how current APP designs, especially in interface color configuration, often fail to...

Visual needs of the elderly in smart app interfaces
Chaya YK

Data analyst intern

October 23, 2024

Summary "Inter-generational effects on the impacts of technology use in later life: Insights from an international, multi-site study."

As technology becomes more common, older adults are also using it more. For many, it helps them stay connected with family, especially children and grandchildren who live far away. They use platforms like Skype, FaceTime...

Impacts of technology use in later life
Soumyadutta Basak

Jr. Bioinformatician

October 09, 2024

Summary "Gene therapy-mediated partial reprogramming extends lifespan and reverses age-related changes in aged mice."

Aging is a major reason for several diseases, driving a high incidence of morbidity and mortality. Cellular rejuvenation is one of the promising methods to counter the damaging effects of aging by reversing epigenetic...

Gene therapy extends lifespan and reverses age-related changes
Vijay Padul

Sr. scientist – Omics

October 09, 2024

Summary "HALL a comprehensive database for human aging and longevity studies."

The study of human aging and longevity is a rapidly evolving field. Various omics technologies are being used to elucidate the aging process and age-related changes in the human body, organs, and cells. Phenomics, Genomics...

Database for human aging and longevity studies
Chaya YK

Data analyst intern

July 03, 2024

Summary "Estimating impact of food choices on life expectancy: A modeling study."

The study investigates the impact of dietary changes on life expectancy (LE), particularly focusing on the transition from a typical Western diet (TW) to a more optimized diet (OD). This research builds on the framework...

Nutritional Cooking
Jay Godara

Research trainee

Jun 26, 2024

Summary "Healthy lifestyle and life expectancy at age 30 years in the Chinese population: An observational study."

Improving health and extending life expectancy are important public health objectives. By 2030, the Healthy China 2030 program hopes to raise the average life expectancy from 76.3 to 79 years. This study looks into...

Healthy lifestyle increases life expectancy
Uma Pala

Research trainee

Jun 19, 2024

Summary "Lower adherence to a Mediterranean diet is associated with high adiposity in community-dwelling older adults: Results from the longevity check-up (lookup) 7+ project."

Excessive fat accumulation is associated with negative health outcomes, which is a major public health concern at all life stages. According to the World Obesity Federation, more than half of the global population will be...

Healthy food
Divyalakshmi

Content writer – Clinical

Jun 12, 2024

Summary "Physical activity has a stronger correlation with arterial stiffness than strength, balance, or BMI in an older population."

Arterial stiffness is associated with several health conditions such as diabetes, hypertension, and cardiovascular diseases. Although it is impossible to stop the natural process of aging, there are factors that may help to slow...

Arterial Stiffness
Shreya Puri

Data analyst intern

Jun 05, 2024

Summary "The effect of long-term care insurance on healthcare utilization of middle-aged and older adults."

The rapid global increase in the aging population has created a significant demand for long-term care (LTC). Developed countries have established LTC insurance (LTCI) systems, providing valuable models for developing...

Long-term care insurance on healthcare utilization
Arya CR

Data analyst intern

May 29, 2024

Summary "Association between healthy eating and depression symptoms among Chinese older adults: A cross-sectional study based on the Chinese Longitudinal Healthy Longevity survey."

This study aimed to assess the relationship between the healthy eating index (HEI) and depression symptoms in an older adult population using the Chinese Longevity Health Survey. Global aging is accelerating, with the...

Depression Symptoms
Soumyadutta Basak

Jr. Bioinformatician

May 22, 2024

Summary "Effects of social participation patterns and living arrangement on mental health of Chinese older adults: A latent class analysis."

According to the World Health Organization, health is a complete state of physical, mental, and social well-being. Mental health is extremely important, especially for older people who, because of physical frailty...

Mental health
Isha Shaw

Data analyst intern

April 17, 2024

Summary "Healthy lifestyle in late-life, longevity genes, and life expectancy among older adults: a 20-year, population-based, prospective cohort study."

The number of people aged 65 years or older is increasing globally, with this group making up 13.5% of China's population. Promoting healthy aging is crucial for individual and societal health. Studies show that following...

Life expectancy among older adults
Jay Darji

Jr. Technical researcher

April 03, 2024

Summary "Systematic Evaluation of machine learning algorithms for neuroanatomically-based age prediction in youth."

Human longevity refers to the actual duration of an individual’s life, and it has been a subject of fascination, study, and speculation throughout human history. Application of machine learning (ML) algorithms to structural...

Machine learning
Vijay Padul

Sr. scientist – Omics

March 27, 2024

Summary "A multi-omic study identifies high confidence genes implicated in biological aging."

Aging-related degenerative diseases are the leading cause of death in developed nations. Current medical interventions are aimed at delaying the onset or treating the symptoms of individual age-related...

Genes implicated in biological aging
Nupur Biswas

Sr. Scientist – Omics

March 20, 2024

Summary "Organ aging signatures in the plasma proteome track health and disease."

As we age our organs also age but not at the same rate. The onset and effects of aging vary from individual to individual. Animal studies showed aging varies within the organs of an individual also. As we age our cells undergo...

Organ aging
Shreya Puri

Data analyst intern

February 28, 2024

Summary "Longevity risk - Its financial impact on pensions."

The research explores the financial impacts of longevity risk on defined benefit (DB) pension plan liabilities in Ghana, utilizing data from the 2010 population census and the Lee-Carter model. It compares two key models...

Longevity and its financial impact
Arya CR

Data analyst intern

February 21, 2024

Summary "Social connectedness, functional capacity, and longevity: A focus on positive relations with others."

Longevity is amongst the complex traits whose genetic foundation is yet unknown. The purpose of this study was to investigate the possible causal relationship and genetic correlation between gut microbiota and...

Social connectedness, functional capacity, and longevit
Soumyadutta Basak

Jr. Bioinformatician

January 31, 2024

Summary "Association between gut microbiota, and longevity: A genetic correlation, and Mendelian randomization study."

Longevity is amongst the complex traits whose genetic foundation is yet unknown. The purpose of this study was to investigate the possible causal relationship and genetic correlation between gut microbiota and...

Gut microbiota
Chaya YK

Data analyst intern

January 17, 2024

Summary "Research on the prediction of longevity from both individual and family perspectives."

This study addresses the growing challenges posed by population aging, particularly in China, where the proportion of elderly individuals has surged. With the elderly constituting a significant demographic, there's an increasing...

Prediction of longevity
Sruthi Chiluveru

Graphic designer

January 03, 2024

Summary "Genetic networks of Alzheimer's disease, Aging and longevity in humans."

Since the 1970s, researchers have suggested that social networks, the connections people have in their daily lives, can impact health. The size, frequency of contact, and diversity of social networks have been...

Genetic networks of Alzheimer's disease
Isha Shaw

Data analyst intern

December 13, 2023

Summary "Social networks, social support, and life expectancy in older adults: the cardiovascular health study."

Since the 1970s, researchers have suggested that social networks, the connections people have in their daily lives, can impact health. The size, frequency of contact, and diversity of social networks have been...

Cardiovascular health study
Yogita Dhas

Content writer – Clinical

December 06, 2023

Summary "Long-term impact of metformin and sulphonylurea therapies on type 2 diabetes: A two-decade analysis of survival patterns."

Metformin is a first-line drug used for type 2 diabetes (T2D) treatment. Metformin has been associated with other non-diabetic health benefits, such as extending a healthy lifespan, in addition to its main use in the treatment...

Long-term effects of metformin on longevity
Jay Darji

Jr. Technical researcher

November 22, 2023

Summary "DeepMAge: A methylation aging clock developed with deep learning."

Human longevity refers to the actual duration of an individual’s life, and it has been a subject of fascination, study, and speculation throughout human history. The quest for understanding and extending the human lifespan...

DeepMAge longevity
Vijay Padul

Sr. scientist – Omics

November 15, 2023

Summary "A multicenter study uncovers genetic factors that may play a significant role in mice longevity."

Aging is a yet to be fully understood process where molecular, cellular, and organismal homeostasis is affected by multiple environmental and genetic factors which results in progressive functional decline in physical

Genetic factors of longevity
Nupur Biswas

Sr. Scientist – Omics

November 08, 2023

Summary "Gene transfer extends lifespan of mice."

Longer lifespan accompanied by a healthy lifespan is always desired. Naked mole rats are the longest-living rodents. They evolved efficient anti-aging and anti-cancer defense. Naked mole-rat tissues are highly...

Gene transfer
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