Nupur Biswas, PhD
Sr. Scientist – Omics
Nupur Biswas is working as a Senior Bioinformatics Scientist at Rhenix. She is working on bioinformatics and other multiple projects as well. Some of her projects include designing personalized neoantigen vaccines for cancer patients and exploring the genes behind Chordoma and the health applications of digital healthcare wearables.
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Nupur has a doctoral degree in Physics and her research work focused on studies of confined polymers. Before joining Rhenix, she worked at the Indian Institute of Science, Raman Research Institute, Kolabtree, and the Indian Institute of Chemical Biology.
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At Rhenix, she has gained experience as not only a research mentor but as a scientist contributing to various international publications.
Summary "Identification of new genetic clusters in Glioblastoma Multiforme: EGFR status and ADD3 losses influence prognosis."
Glioblastoma (GB) multiforme, IDH wild-type (GB-IDHwt) is the most frequent brain tumor with poor survival rate. Glioblastoma with mutant IDH enzyme shows good prognosis. The highly genetic heterogeity is responsible…
Summary "Organ aging signatures in the plasma proteome track health and disease."
As we age our organs also age but not at the same rate. The onset and effects of aging vary from individual to individual. Animal studies showed aging varies within the organs of an individual also. As we age our cells undergo...
Summary "Investigating nutrient biomarkers of healthy brain aging: A multimodal brain imaging study."
Aging is associated with a gradual loss of physiological integrity along with cognitive impairment. It induces impaired function of organs with vulnerability to death. Our cognitive performances and brain functions also decline.
Videos
EGFR status determines GB subtypes | Cell talk
Glioblastoma (GB) multiforme, IDH wild-type (GB-IDHwt) is the most frequent brain tumor with a poor survival rate. Glioblastoma with mutant IDH enzyme shows a good prognosis. The highly genetic heterogeity is responsible for the absence of...
Somatic mutations in Alzheimer’s disease neurons | Cell talk
Alzheimer’s disease (AD) is a common age-associated neurodegenerative disorder. It is associated with the deposition of amyloid-beta oligomers and tau proteins. However, the underneath cellular dysfunction...
Identifying candidate Parkinson's disease genes by integrating genomic data | Cell talk
Parkinson’s disease (PD) is a neurological disorder observed mostly in elderly individuals. The symptoms include tremors, muscle stiffness, slow motion, and loss of balance. It is caused when neurons of the basal ganglia region of the brain fail to...
Circular RNAs in diagnosis of Astrocytoma | Cell talk
Astrocytoma is a type of brain tumor associated with astrocytes. Grade IV astrocytoma is commonly known as glioblastoma. Molecular-based diagnosis is challenging as it requires brain surgery for obtaining tissue samples/specimens...
Role of air pollutants in lung cancer | Cell talk
Lung cancer in never-smokers (LCINS) is the eighth most common cause of cancer death in the UK. Such patients bear distinct clinical and molecular characteristics compared to lung cancer in smokers which include EGFR mutations. The current study explores...
Gene transfer extends lifespan of mice | Cell talk
Longer lifespan accompanied by healthy lifespan is always desired. Naked mole rats are the longest living rodents. They evolved efficient anti-aging and anti-cancer defense. Naked mole-rat tissues are highly enriched for high molecular weight hyaluronic...
Longevity: Determining factors | Cell talk
The goal of the longevity research is understanding the aging process and tune it. For the quest of longevity, researchers identified nine hallmarks of aging which include genomic instability, telomere attrition...
Longevity: How far can we stretch it | Cell talk
The basic question of longevity is how long a human can live. The increasing number of centenarians indicates an increase in the average lifespan. To date, based on the available and reliable documents, the longest-living person was of age 122 years...
Lifespan or healthspan which is your goal | Cell talk
Lifespan refers to the time a person lives. On the other hand, healthspan refers to the time during which a person lives a healthy life without any chronic disease and age-related disorders. However, defining a healthy life...
Organ aging signatures in the plasma proteome track health and disease | Cell talk
As we age our organs also age but not at the same rate. The onset and effects of aging vary from individual to individual. Animal studies showed aging varies within the organs of an individual also. As we age our cells undergo...
Lifestyle factors affecting longevity | Cell talk
Longevity is determined by a combination of genetic and non-genetic factors. It is shown that genetic variations cause about 25% of variation in longevity. On the other hand, non-genetic factors include lifestyle and...
Investigating nutrient biomarkers of healthy brain aging: A multimodal brain imaging study | Cell talk
Aging is associated with a gradual loss of physiological integrity along with cognitive impairment. It induces impaired function of organs with vulnerability to death. Our cognitive performances and brain functions also decline. It is caused...
