The study, "Elderly-Centric Chromatics: Unraveling the Color Preferences and Visual Needs of the Elderly in Smart APP Interfaces," addresses how current APP designs, especially in interface color configuration, often fail to meet the specific needs of elderly users, who experience visual fatigue and reduced color discrimination due to aging. Although research has explored various aspects of human-computer interaction (HCI) for the elderly, there is a significant gap in creating color configuration standards that align with their physiological characteristics. Most studies focus on interaction design and icon cognition but overlook age-related visual impairments. This gap underscores the need for focused research and development in this area to improve the accessibility and usability of design for older users. Methodology: The research employs the Hue, Saturation, and Lightness (HSL) color model and integrates methodologies from color theory, psychology, and design. For elderly users, the design must consider their reduced visual acuity and color discernment. Effective designs should emphasize easily recognizable colors and clear contrasts, using a combination of primary, standard, and accent colors to enhance object identification and interface navigation. This approach ensures a user-friendly experience tailored to the visual needs of older adults. Results: The results revealed that elderly users significantly prefer warm hues (yellow, orange), medium saturation, and high lightness. Cooler hues, such as blue and purple, were disliked, as they evoked feelings of coldness and loneliness. High lightness improved text readability and object recognition, while medium saturation provided visual comfort without overwhelming the users. The study also highlighted the negative effects of low-lightness or over-saturated colors on elderly users, which could lead to increased visual fatigue and reduced interface usability. Conclusion: In conclusion, this article presents a comprehensive approach to designing age-friendly APP interfaces for the elderly, namely optimizing color configurations based on the visual characteristics and needs of the elderly. The research identifies a preference among elderly users for warm hue colors, medium saturation, and high lightness, suggesting that the color configuration of the APP interface that meets these parameters contribute to elderly users achieve a more comfortable and efficient experience. This preference is attributed to the aging-related changes in visual acuity and color perception. Impact of Research: The research holds significant implications for designing user-friendly and inclusive interfaces, particularly as global populations continue to age. By aligning app designs with the visual needs of the elderly, developers can improve accessibility and overall user satisfaction. The findings of the study serve as a guide for app developers and designers to create better products that support the elderly’s interaction with technology, ultimately enhancing their quality of life.