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Researchs

Discover new pieces of information with our RESEARCH

Yogita Dhas.jpg

Content writer – Clinical

April 12, 2023

Summary "Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas."

Meningiomas are the most prevalent primary central nervous system tumor, with a prevalence of 170,000 cases in the United States. Maximal safe resection is the cornerstone of meningioma treatment, and...

Meningioma.jpg
jay darji.jpg

Jr. technical researcher

November 16, 2022

Summary "A hybrid CNN-GLCM classifier for detection and grade classification of brain tumor."

A tumor is a volume of irregular and abnormal cells affecting the function of nearby healthy cells in the human body. Meningioma is the most commonly occurring tumor in adults with high-risk factors...

Meningioma.jpg
Vijay Padul

Sr. scientist - Omics

March 15, 2023

Summary "Multi-omic analysis of low-grade glioma histological subtypes uncovers the significance of tumor purity."

Astrocytoma and Oligodendroglioma are the histological subtypes of glioma brain tumors. Histological classification of gliomas has been the clinical practice before the inclusion of molecular markers by the...

Astrocytoma.jpg
Isha Shaw.jpg

Proofreading intern

March 07, 2023

Summary "Quality of YouTube videos on meningioma treatment using the DISCERN instrument."

Meningiomas are the most common type of primary brain tumor that arises from the brain or the spinal cord. Although the majority of meningiomas are benign, these tumors can cause problems as they grow...

Quality of YouTube videos on meningioma treatment using the DISCERN instrument.jpg
Nupur Biswas, PhD.jpg

Sr. scientist – Omics

March 01, 2023

Summary "Circular RNAs in Diagnosis of Astrocytoma."

Astrocytoma is a type of brain tumor associated with astrocytes. Grade IV astrocytoma is commonly known as glioblastoma. Molecular-based diagnosis is challenging as it requires brain surgery for obtaining...

Circular RNAs in Diagnosis of Astrocytoma.jpg
Bharati.jpg

Content writer – Clinical

February 15, 2023

Summary "Expression of   CD133 cancer stems cell marker in IDH-mutant and IDH-wild type (isocitrate dehydrogenase) astrocytoma."

Astrocytoma is a tumor that arises from the astrocytes. They belong to a group called glial cells, the supporting cells seen in the central nervous system. They are specifically called astrocytes when they are...

Expression of   CD133 cancer stem cell marker in IDH-mutant and IDH-wild type (isocitrate
Divyalakshmi.jpg

Content writer – Clinical

February 08, 2023

Summary "Prognostic factors associated with survival in patients with diffuse astrocytoma."

Astrocytomas are the most common primary tumors in the central nervous system (CNS). These tumors arise from astrocytes—star-shaped cells that make up the “glue-like” or supportive tissue of the brain. The diagnosis is based...

Astrocytoma.jpg
Aditi Ratnam.jpg

Proofreading intern

February 07, 2023

Summary "Brain tumor patients’ use of social media for disease management: Current practices and implications for the future."

Brain tumor-related diseases are some of the longest and most painful ailments worldwide, and their symptoms lead to social and physical isolation. This study is based on the patients who were administered a questionnaire...

Social media
Numair Arshad.jpg

Content writer – Clinical

February 01, 2023

Summary "Exploring the safety and efficacy of a novel drug combination for treating recurrent high-grade astrocytomas: A phase 1 clinical trial."

Astrocytoma is a type of brain tumor that originates from star-shaped glial cells in the brain called astrocytes. According to the WHO classification, they are classified into four grades based on the degree of malignancy and...

Astrocytoma.jpg
Yogita Dhas.jpg

Content writer – Clinical

January 17, 2023

Summary "Grading of IDH‑mutant astrocytoma using diffusion, susceptibility, and perfusion‑weighted imaging."

The accurate grading of IDH-mutant astrocytoma is essential to develop therapeutic strategies and evaluating the prognosis of patients. A preoperative classification of these entities could be beneficial for the treatments...

Astrocytoma
Vijay Padul

Sr. scientist - Omics

January 11, 2023

Summary "An effective integrated grading system for meningioma tumour grading that incorporates molecular features."

Meningioma is the most common primary intracranial tumor in the United States. There are approximately 35,000 new cases diagnosed every year. Meningioma has an estimated population prevalence of approximately...

Meningioma
Aditi Ratnam.jpg

Proofreading intern

January 10, 2023

Summary "How mental health care should change as a consequence of the COVID-19 pandemic?"

As the world went from having the busiest streets to empty ones, lives were changed all around in 2020. The coronavirus or Covid-19 more formally known as SARS-CoV-2 was first discovered in Wuhan, China in December...

COVID-19.jpg
Abhijeet.jpg

Jr. Economist intern

December 20, 2022

Summary "Caste differences in hypertension among women in India: diminishing health returns to socioeconomic status for lower caste groups."

The caste system is a relatively rigid system of social hierarchy in India. Caste membership defines one’s access to resources and life opportunities. A growing body of research suggests that lower caste...

Caste differences in hypertension among women in India.jpg
Ishita Narvekar.jpg

Jr. Economist intern

December 13, 2022

Summary "Dietary intake of Parkinson's disease patients."

Parkinson's disease is the second most prevalent neurodegenerative disorder. Often, dietary management is supplemented as adjuvant therapy. Therefore, dietary relevant studies may grant an interesting...

Parkinson's disease.jpg
jay darji.jpg

Jr. technical researcher

November 16, 2022

Summary "A comparative analysis of machine learning algorithms to predict Alzheimer’s disease."

Alzheimer's disease is a progressive neurological disorder that causes brain cells to die and the brain to shrink (atrophy). Alzheimer's disease is the most common cause of dementia, which is defined as a progressive decline...

Alzheimer’s disease.jpg
Bharati.jpg

Content writer – Clinical

November 09, 2022

Summary "High frequency of psychosis in late-stage Parkinson's disease."

Parkinson’s disease (PD) is a neurological disorder observed mostly in elderly individuals. The symptoms include tremors, muscle stiffness, slow motion, and loss of balance. It is caused when neurons of the basal ganglia region...

Parkinson's disease.jpg
Divyalakshmi.jpg

Content writer – Clinical

November 02, 2022

Summary "Reassessing Diabetes and APOE Genotype as Potential Interacting Risk Factors for Alzheimer’s disease."

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder in which the death of brain cells causes memory loss and cognitive decline. Alzheimer's disease is the most common cause of dementia...

Alzheimer's disease.jpg
Aditi Ratnam.jpg

Proofreading intern

November 01, 2022

Summary "YouTube as a Source of Information for Neurosurgery."

Social Media is an important part of our daily lives; statistically, it has been so for the last two centuries. We have evolved from the invention of the telegraph in 1844 (where messages were transmitted physically...

Digital Healthcare.jpg
Numair Arshad.jpg

Content writer – Clinical

October 25, 2022

Summary "Slowing down Alzheimer’s disease by combining an anti-oxidant drug, GV1001, with donepezil."

Alzheimer’s disease (AD) is a neurodegenerative disease that impairs short-term memory and affects the judgment and behavior of the patient. Brain cells continue to die as time passes and the patient eventually...

Alzheimer's disease.jpg
Nupur Biswas, PhD.jpg

Sr. scientist – Omics

October 19, 2022

Summary "Identifying candidate Parkinson's disease genes by integrating genomic data."

Parkinson’s disease (PD) is a neurological disorder observed mostly in elderly individuals. The symptoms include tremors, muscle stiffness, slow motion, and loss of balance. It is caused when neurons...

Parkinson's disease.jpg
Yogita Dhas.jpg

Content writer – Clinical

October 18, 2022

Summary "A six-metabolite panel as potential blood-based biomarkers for Parkinson’s disease."

Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease (AD) and affects around five million people worldwide. People with PD typically exhibit symptoms when 50% or more...

Parkinson's disease.jpg
Jhivir Kapoor.jpg

Jr. Economist intern

October 12, 2022

Summary "Economic Burden of Alzheimer’s Disease Dementia in Japan."

Alzheimer’s disease dementia (ADD) is the leading cause of long-term care in Japan. In Japan, the number of older adults aged 65 years or over, living with dementia was estimated to be 4,620,000 in 2012. In a projection using data...

Alzheimer's disease.jpg
Shaheen Shah.jpg

Content writer – Clinical

October 11, 2022

Summary "Triggers and alleviating factors for fatigue in Parkinson's disease."

Parkinson's disease (PD) is a progressive disorder that affects the nervous system. Symptoms start slowly. The first symptom may be a barely noticeable tremor in just one hand. Tremors are typical, but the disorder...

Parkinson's disease.jpg
Vijay Padul

Sr. scientist - Omics

October 07, 2022

Summary "Uncovering the link between chromatin activity, gene expression in myeloid cells and Alzheimer’s disease risk."

Alzheimer’s disease (AD) is a progressive neurological disorder commonly affecting people older than 65 years of age. The neurodegenerative progression of the disorder...

Alzheimer's disease
Ishita Narvekar.jpg

Jr. Economist intern

September 28, 2022

Summary "Association of multidimensional poverty with dementia in adults aged 50 years or older in South Africa"

Dementia has become a global health challenge. It is well documented that poor social determinants of health are directly associated with the disease. Hence a multidimensional approach to poverty...

Healthcare economics - IN.jpg
Abhijeet.jpg

Jr. Economist intern

September 21, 2022

Summary "Caste, Religion, and Mental Health in India"

A large, multi-disciplinary literature in social epidemiology, public health, and medical sociology has been concerned with documenting and understanding disparities in health by race, ethnicity, gender, socioeconomic...

Healthcare economics.jpg
Nupur Biswas

Sr. scientist – Omics

September 14, 2022

Summary "Somatic mutations in Alzheimer’s disease neurons"

Alzheimer’s disease (AD) is a common age-associated neurodegenerative disorder. It is associated with the deposition of amyloid-beta oligomers and tau proteins. However, the underneath cellular dysfunction is...

Alzheimer's disease.jpg
Sowmya Shivarama.jpg

Content writer – Clinical

August 19, 2022

Summary "Targeting the αv integrin/TGF-β axis improves natural killer cell function against Glioblastoma stem cells | CellTalk"

Glioblastoma multiform (GBM), the most aggressive brain cancer, recurs due to the resistance of glioblastoma stem cells (GSCs) to all standard therapies. This dismal therapy outcome has sparked intense interest in immunotherapy...

Glioblastoma Multiforme -SS.jpg
Jhivir Kapoor.jpg

Jr. Economist intern

August 12, 2022

Summary "Comparing the average cost of outpatient care of public and for-profit private providers in India | CellTalk"

In mixed healthcare systems like India's, it is crucial to understand the cost of care associated with various types of healthcare providers to influence policy discussions. Existing studies reporting Out of Pocket Expenditure...

Healthcare economics - JK.jpg
Numair Arshad.jpg

Content writer – Clinical

August 05, 2022

Summary "Slowing down glioma growth by knocking out miR-21 in mice models"

Glioblastoma multiforme (GBM) is an aggressive form of glioma with a median survival of 15 months. Heterogeneity is one of the main characteristics of GBM. The tumor cells show variability not only from one patient...

Glioblastoma Multiforme - NA.jpg
Divyalakshmi.jpg

Content writer – Clinical

July 29, 2022

Summary "Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of Glioblastoma"

Glioblastoma multiforme (GBM) is the most common and aggressive form of primary brain cancer in adults. It accounts for about 60-70% of gliomas. The standard treatment regimen for GBM is tumor resection followed...

Glioblastoma Multiforme - DR.jpg
Ishita Narvekar.jpg

Jr. Economist intern

July 22, 2022

Summary "Health and its impact on economic growth in India – An explanation"

The role of ‘human capital’ in economic growth is vital. An economy that depends on human capital is now widely accepted. A higher level of human capital is the result of a higher level of health status, better health education...

Healthcare economics - IN.jpg
Swetha Chakrabarthi

Jr. scientist – Omics

July 15, 2022

Summary "Multifunctional silica-coated mixed polymeric micelles for integrin-targeted therapy of pediatric patient-derived Glioblastoma."

Glioblastoma (GBM) is the malignant brain tumor of the primary central nervous system (CNS) arising from the glial cells having an incidence ranging from 5 to 8 persons per 100,000 individuals...

Glioblastoma Multiforme- SC.jpg
Vijay Padul

Sr. scientist - Omics

June 29, 2022

Summary "A phase Ib-IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma- CUSP9v3-2021"

Glioblastoma is the most common and aggressive primary malignant brain tumor in adults. Despite therapeutic interventions, glioblastoma prognosis remains very poor as most patients die…

Glioblastoma Multiforme - VP.jpg
Nupur Biswas

Sr. scientist – Omics

June 24, 2022

Summary "Identification of new Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis"

Glioblastoma (GB) multiforme, IDH wild-type (GB-IDHwt) is the most frequent brain tumor with poor survival rate. Glioblastoma with mutant IDH enzyme shows good prognosis. The highly genetic heterogeity is responsible…

Glioblastoma Multiforme - NB.jpg
Souvik Datta

Content writer – Clinical

June 16, 2022

Summary "Effects of metformin as an add-on therapy against Glioblastoma: an old medicine for Novel Oncology Therapeutics"

Medical research is focused on finding solutions through diligent and innovative platforms in the field of health and disease. Every published paper holds a stepping stone toward gaining knowledge…

Glioblastoma Multiforme
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